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Epigenetic regulation of the 1,25-dihydroxyvitamin D(3) 24-hydroxylase (CYP24A1) in colon cancer cells

Calcitriol is the hormonally active form of vitamin D and has anti-proliferative and pro-apoptotic effects. Calcitriol and its precursor calcidiol (25(OH)D(3)) are degraded by the 1,25-dihydroxyvitamin D(3) 24-hydroxylase (CYP24A1). This enzyme is overexpressed in colorectal tumors, however, the mec...

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Detalles Bibliográficos
Autores principales:	Höbaus, Julia, Fetahu, Irfete Sh., Khorchide, Maya, Manhardt, Teresa, Kallay, Enikö
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pergamon 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695570/ https://www.ncbi.nlm.nih.gov/pubmed/22940288 http://dx.doi.org/10.1016/j.jsbmb.2012.08.003

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