Cargando…

Stable tumor vessel normalization with pO(2) increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment

Tumor hypoxia is a characteristic of cancer cell growth and invasion, promoting angiogenesis, which facilitates metastasis. Oxygen delivery remains impaired because tumor vessels are anarchic and leaky, contributing to tumor cell dissemination. Counteracting hypoxia by normalizing tumor vessels in o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kieda, Claudine, El Hafny-Rahbi, Bouchra, Collet, Guillaume, Lamerant-Fayel, Nathalie, Grillon, Catherine, Guichard, Alan, Dulak, Jozef, Jozkowicz, Alicja, Kotlinowski, Jerzy, Fylaktakidou, Konstantina C., Vidal, Aurélien, Auzeloux, Philippe, Miot-Noirault, Elisabeth, Beloeil, Jean-Claude, Lehn, Jean-Marie, Nicolau, Claude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695680/ https://www.ncbi.nlm.nih.gov/pubmed/23471434 http://dx.doi.org/10.1007/s00109-013-0992-6

Ejemplares similares

Tumour angiogenesis normalized by myo‐inositol trispyrophosphate alleviates hypoxia in the microenvironment and promotes antitumor immune response
por: El Hafny‐Rahbi, Bouchra, et al.
Publicado: (2021)

Treatment of hypoxia‐dependent cardiovascular diseases by myo‐inositol trispyrophosphate (ITPP)‐enhancement of oxygen delivery by red blood cells
por: Oknińska, Marta, et al.
Publicado: (2020)

Tumor hypoxia modulates podoplanin/CCL21 interactions in CCR7+ NK cell recruitment and CCR7+ tumor cell mobilization
por: Tejchman, Anna, et al.
Publicado: (2017)

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia
por: Carreau, Aude, et al.
Publicado: (2011)

Phase Ib dose-escalation study of the hypoxia-modifier Myo-inositol trispyrophosphate in patients with hepatopancreatobiliary tumors
por: Schneider, Marcel A., et al.
Publicado: (2021)

Tumour suppressor PTEN activity is differentially inducible by myo‐inositol phosphates
por: Grzymajlo, Krzysztof, et al.
Publicado: (2023)

Hypoxia-shaped vascular niche for cancer stem cells
por: Collet, Guillaume, et al.
Publicado: (2015)

Spheroid-plug model as a tool to study tumor development, angiogenesis, and heterogeneity in vivo
por: Szade, Krzysztof, et al.
Publicado: (2015)

Oxygen therapeutic window induced by myo-inositol trispyrophosphate (ITPP)–Local pO(2) study in murine tumors
por: Krzykawska-Serda, Martyna, et al.
Publicado: (2023)

Differential Effects of Bartonella henselae on Human and Feline Macro- and Micro-Vascular Endothelial Cells
por: Berrich, Moez, et al.
Publicado: (2011)

Effect of Heme Oxygenase-1 on Melanoma Development in Mice—Role of Tumor-Infiltrating Immune Cells
por: Was, Halina, et al.
Publicado: (2020)

Right ventricular myocardial oxygen tension is reduced in monocrotaline-induced pulmonary hypertension in the rat and restored by myo-inositol trispyrophosphate
por: Oknińska, Marta, et al.
Publicado: (2021)

Regulation and Novel Action of Thymidine Phosphorylase in Non-Small Cell Lung Cancer: Crosstalk with Nrf2 and HO-1
por: Tertil, Magdalena, et al.
Publicado: (2014)

Targeted Radionuclide Therapy Decreases Melanoma Lung Invasion by Modifying Epithelial-Mesenchymal Transition-Like Mechanisms()
por: Akil, Hussein, et al.
Publicado: (2019)

PPAR Gamma and Angiogenesis: Endothelial Cells Perspective
por: Kotlinowski, Jerzy, et al.
Publicado: (2016)

Myoblast-conditioned media improve regeneration and revascularization of ischemic muscles in diabetic mice
por: Kozakowska, Magdalena, et al.
Publicado: (2015)

Impact of myo‐inositol trispyrophosphate (ITPP) on tumour oxygenation and response to irradiation in rodent tumour models
por: Tran, Ly‐Binh‐An, et al.
Publicado: (2018)

A“Proteoglycan Targeting Strategy” for the Scintigraphic Imaging and Monitoring of the Swarm Rat Chondrosarcoma Orthotopic Model
por: Peyrode, Caroline, et al.
Publicado: (2011)

(99m)Tc-NTP 15-5 is a companion radiotracer for assessing joint functional response to sprifermin (rhFGF-18) in a murine osteoarthritis model
por: Briat, Arnaud, et al.
Publicado: (2022)

Heme Oxygenase-1 Accelerates Cutaneous Wound Healing in Mice
por: Grochot-Przeczek, Anna, et al.
Publicado: (2009)

Development of a methodology for in vivo follow-up of hepatocellular carcinoma in hepatocyte specific Trim24-null mice treated with myo-inositol trispyrophosphate
por: Ignat, Mihaela, et al.
Publicado: (2016)

Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy()
por: Rbah-Vidal, Latifa, et al.
Publicado: (2016)

La soudure à l'arc électrique: des principes aux applications
por: Guichard, Jean-Claude
Publicado: (2013)

TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation
por: Loboda, Agnieszka, et al.
Publicado: (2016)

PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors
por: Kotlinowski, Jerzy, et al.
Publicado: (2014)

The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes
por: Kozakowska, Magdalena, et al.
Publicado: (2016)

Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing
por: Voissiere, Aurélien, et al.
Publicado: (2017)

Erratum: PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors
por: Kotlinowski, Jerzy, et al.
Publicado: (2015)

Phase I study of [(131)I] ICF01012, a targeted radionuclide therapy, in metastatic melanoma: MELRIV-1 protocol
por: Thivat, Emilie, et al.
Publicado: (2022)

Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models
por: Rondon, Aurélie, et al.
Publicado: (2017)

Aristolochic acid I and ochratoxin A differentially regulate VEGF expression in porcine kidney epithelial cells—The involvement of SP-1 and HIFs transcription factors
por: Stachurska, Anna, et al.
Publicado: (2011)

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
por: Loboda, Agnieszka, et al.
Publicado: (2016)

Heme oxygenase inhibition in cancers: possible tools and targets
por: Podkalicka, Paulina, et al.
Publicado: (2018)

Haeme oxygenase protects against UV light DNA damages in the retina in clock-dependent manner
por: Damulewicz, Milena, et al.
Publicado: (2017)

Interactions Between the Circadian Clock and Heme Oxygenase in the Retina of Drosophila melanogaster
por: Damulewicz, Milena, et al.
Publicado: (2016)

Activity of MCPIP1 RNase in tumor associated processes
por: Miekus, Katarzyna, et al.
Publicado: (2019)

The Role of miR-378a in Metabolism, Angiogenesis, and Muscle Biology
por: Krist, Bart, et al.
Publicado: (2015)

Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression
por: Brassart-Pasco, Sylvie, et al.
Publicado: (2020)

The role of hypoxia in shaping the recruitment of proangiogenic and immunosuppressive cells in the tumor microenvironment
por: Chouaib, Salem, et al.
Publicado: (2018)

The Polyphenol Fisetin Protects Bone by Repressing NF-κB and MKP-1-Dependent Signaling Pathways in Osteoclasts
por: Léotoing, Laurent, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_118n39e3fh2vdu6av2btgevqql