Lenticular mitoprotection. Part A: Monitoring mitochondrial depolarization with JC-1 and artifactual fluorescence by the glycogen synthase kinase-3β inhibitor, SB216763

PURPOSE: Dissipation of the electrochemical gradient across the inner mitochondrial membrane results in mitochondrial membrane permeability transition (mMPT), a potential early marker for the onset of apoptosis. In this study, we demonstrate a role for glycogen synthase kinase-3β (GSK-3β) in regulat...

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Detalles Bibliográficos
Autores principales: Brooks, Morgan M., Neelam, Sudha, Fudala, Rafal, Gryczynski, Ignacy, Cammarata, Patrick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695757/
https://www.ncbi.nlm.nih.gov/pubmed/23825920

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