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The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6

BACKGROUND: Expression of the cellular karyopherin TNPO3/transportin-SR2/Tnp3 is necessary for HIV-1 infection. Depletion of TNPO3 expression in mammalian cells inhibits HIV-1 infection after reverse transcription but prior to integration. RESULTS: This work explores the role of cleavage and polyade...

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Detalles Bibliográficos
Autores principales:	Fricke, Thomas, Valle-Casuso, Jose Carlos, White, Tommy E, Brandariz-Nuñez, Alberto, Bosche, William J, Reszka, Natalia, Gorelick, Robert, Diaz-Griffero, Felipe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695788/ https://www.ncbi.nlm.nih.gov/pubmed/23622145 http://dx.doi.org/10.1186/1742-4690-10-46

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