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Bone Morphogenetic Proteins Stimulate Mammary Fibroblasts to Promote Mammary Carcinoma Cell Invasion

Bone Morphogenetic Proteins (BMPs) are secreted cytokines that are part of the Transforming Growth Factor β (TGFβ) superfamily. BMPs have been shown to be highly expressed in human breast cancers, and loss of BMP signaling in mammary carcinomas has been shown to accelerate metastases. Interestingly,...

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Detalles Bibliográficos
Autores principales: Owens, Philip, Polikowsky, Hannah, Pickup, Michael W., Gorska, Agnieszka E., Jovanovic, Bojana, Shaw, Aubie K., Novitskiy, Sergey V., Hong, Charles C., Moses, Harold L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695869/
https://www.ncbi.nlm.nih.gov/pubmed/23840733
http://dx.doi.org/10.1371/journal.pone.0067533