Cargando…

Enhanced Active Targeting via Cooperative Binding of Ligands on Liposomes to Target Receptors

To achieve effective active targeting in a drug delivery system, we previously developed dual-targeting (DT) liposomes decorated with both vascular endothelial growth factor receptor-1 (VEGFR-1)-targeted APRPG and CD13-targeted GNGRG peptide ligands for tumor neovessels, and observed the enhanced su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sugiyama, Tomoki, Asai, Tomohiro, Nedachi, Yuki Murase, Katanasaka, Yasufumi, Shimizu, Kosuke, Maeda, Noriyuki, Oku, Naoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695877/ https://www.ncbi.nlm.nih.gov/pubmed/23840738 http://dx.doi.org/10.1371/journal.pone.0067550

Ejemplares similares

Liposomes and nanotechnology in drug development: focus on ocular targets
por: Honda, Miki, et al.
Publicado: (2013)

Bauhinia purprea agglutinin‐modified liposomes for human prostate cancer treatment
por: Ikemoto, Keisuke, et al.
Publicado: (2015)

Enhanced Efficacy of Doxorubicin by microRNA-499-Mediated Improvement of Tumor Blood Flow
por: Okamoto, Ayaka, et al.
Publicado: (2016)

Targeted Therapy for Acute Autoimmune Myocarditis with Nano-Sized Liposomal FK506 in Rats
por: Okuda, Keiji, et al.
Publicado: (2016)

Liposomal Tumor Targeting in Drug Delivery Utilizing MMP-2- and MMP-9-Binding Ligands
por: Penate Medina, Oula, et al.
Publicado: (2011)

Use of Positron Emission Tomography for Real-Time Imaging of Biodistribution of Green Tea Catechin
por: Shimizu, Kosuke, et al.
Publicado: (2014)

Application and Utility of Liposomal Neuroprotective Agents and Biomimetic Nanoparticles for the Treatment of Ischemic Stroke
por: Fukuta, Tatsuya, et al.
Publicado: (2022)

Enhanced immunocompatibility of ligand-targeted liposomes by attenuating natural IgM absorption
por: Guan, Juan, et al.
Publicado: (2018)

Cooperative kinetics of ligand binding to linear polymers
por: Villaluenga, Juan P.G., et al.
Publicado: (2022)

Non-invasive evaluation of neuroprotective drug candidates for cerebral infarction by PET imaging of mitochondrial complex-I activity
por: Fukuta, Tatsuya, et al.
Publicado: (2016)

Modifying glycyrrhetinic acid liposomes with liver-targeting ligand of galactosylated derivative: preparation and evaluations
por: Chen, Jing, et al.
Publicado: (2017)

Increased Targeting Area in Tumors by Dual-Ligand Modification of Liposomes with RGD and TAT Peptides
por: Amin, Mohamadreza, et al.
Publicado: (2022)

A Liposomal Drug Platform Overrides Peptide Ligand Targeting to a Cancer Biomarker, Irrespective of Ligand Affinity or Density
por: Gray, Bethany Powell, et al.
Publicado: (2013)

Predicting target-ligand interactions using protein ligand-binding site and ligand substructures
por: Wang, Caihua, et al.
Publicado: (2015)

Peptide ligand and PEG-mediated long-circulating liposome targeted to FGFR overexpressing tumor in vivo
por: Cai, Lulu, et al.
Publicado: (2012)

Rationalizing Tight Ligand Binding through Cooperative Interaction Networks
por: Kuhn, Bernd, et al.
Publicado: (2011)

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin
por: Cheng, Mu, et al.
Publicado: (2014)

The Evidence of Cooperative Binding of a Ligand to G4 DNA
por: Kudrev, A. G.
Publicado: (2017)

Ligand design by targeting a binding site water
por: Matricon, Pierre, et al.
Publicado: (2020)

Effects of Polyethylene Glycol Spacer Length and Ligand Density on Folate Receptor Targeting of Liposomal Doxorubicin In Vitro
por: Kawano, Kumi, et al.
Publicado: (2011)

Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt
por: de Vries, Rens M. J. M., et al.
Publicado: (2021)

Discovery of Novel Small Molecules for Heart Failure Therapy Using Cultured Cardiomyocyte by High Throughput Screening Assay
por: Shimizu, Satoshi, et al.
Publicado: (2021)

Mannosylated liposomes for targeted gene delivery
por: Kong, Fansheng, et al.
Publicado: (2012)

Ligation Strategies for Targeting Liposomal Nanocarriers
por: Marqués-Gallego, Patricia, et al.
Publicado: (2014)

Lung targeted liposomes for treating ARDS
por: Arber Raviv, Sivan, et al.
Publicado: (2022)

Oncogenic Y‐box binding protein‐1 as an effective therapeutic target in drug‐resistant cancer
por: Kuwano, Michihiko, et al.
Publicado: (2019)

Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3
por: Freichel, Tanja, et al.
Publicado: (2019)

To bind or not to bind – how to down-regulate target genes by liganded thyroid hormone receptor?
por: Weitzel, Joachim M
Publicado: (2008)

Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases
por: Shimizu, Kana, et al.
Publicado: (2019)

The Polyunsaturated Fatty Acids EPA and DHA Prevent Myocardial Infarction-induced Heart Failure by Inhibiting p300-HAT Activity in Rats
por: Sunagawa, Yoichi, et al.
Publicado: (2021)

Young Investigator Award: Compound A, a Ginger Extract, Significantly Reduces Pressure Overload-induced Systolic Heart Failure in Mice
por: Kawase, Yuto, et al.
Publicado: (2021)

Targeting the tumor microenvironment by liposomal Epacadostat in combination with liposomal gp100 vaccine
por: Tahaghoghi-Hajghorbani, Sahar, et al.
Publicado: (2023)

Membrane Interaction of Bound Ligands Contributes to the Negative Binding Cooperativity of the EGF Receptor
por: Arkhipov, Anton, et al.
Publicado: (2014)

Metastasis of Breast Cancer Promoted by Circadian Rhythm Disruption due to Light/Dark Shift and its Prevention by Dietary Quercetin in Mice
por: Numata, Minoru, et al.
Publicado: (2021)

Lipidated Peptidomimetic Ligand-Functionalized HER2 Targeted Liposome as Nano-Carrier Designed for Doxorubicin Delivery in Cancer Therapy
por: Naik, Himgauri, et al.
Publicado: (2021)

Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets
por: Beno, Itai, et al.
Publicado: (2011)

Cooperative ligand binding to a double-stranded Ising lattice—Application to cofilin binding to actin filaments
por: Cao, Wenxiang, et al.
Publicado: (2023)

Amadori-glycated phosphatidylethanolamine enhances the physical stability and selective targeting ability of liposomes
por: Miyazawa, Taiki, et al.
Publicado: (2018)

Thermodynamic analysis of cooperative ligand binding by the ATP-binding DNA aptamer indicates a population-shift binding mechanism
por: Slavkovic, Sladjana, et al.
Publicado: (2020)

Tumor targeting using liposomal antineoplastic drugs
por: Huwyler, Jörg, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_8r27telrj78ivvfv4bgt7u7m2n