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A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis

BACKGROUND: The unfolded protein response (UPR) is a major signalling cascade acting in the quality control of protein folding in the endoplasmic reticulum (ER). The cascade is known to play an accessory role in a range of genetic and environmental disorders including neurodegenerative and cardiovas...

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Detalles Bibliográficos
Autores principales:	Erguler, Kamil, Pieri, Myrtani, Deltas, Constantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695880/ https://www.ncbi.nlm.nih.gov/pubmed/23433609 http://dx.doi.org/10.1186/1752-0509-7-16

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