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Pyruvate Kinase M2 Plays a Dual Role on Regulation of the EGF/EGFR Signaling via E-Cadherin-Dependent Manner in Gastric Cancer Cells
BACKGROUND AND AIMS: EGFR activation and PKM2 expression are instrumental in tumorigenesis. EGFR activation regulates PKM2 functions in a subcellular compartment-dependent manner and promotes gene transcription and tumor growth. In addition, PKM2 is upregulated in EGFR-induced pathways in glioma mal...
Autores principales: | Wang, Le-Yi, Liu, Yun-Peng, Chen, Li-Gang, Chen, Yan-Ling, Tan, Li, Liu, Jing-Jing, Jazag, Amarsanaa, Ren, Jian-Lin, Guleng, Bayasi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695906/ https://www.ncbi.nlm.nih.gov/pubmed/23840737 http://dx.doi.org/10.1371/journal.pone.0067542 |
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