Extensive Variation in Gene Copy Number at the Killer Immunoglobulin-Like Receptor Locus in Humans

Killer immunoglobulin-like receptors (KIRs) are involved in the regulation of natural killer cell cytotoxicity. Within the human genome seventeen KIR genes are present, which all contain a large number of allelic variants. The high level of homology among KIR genes has hampered KIR genotyping in lar...

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Detalles Bibliográficos
Autores principales: Vendelbosch, Sanne, de Boer, Martin, Gouw, Remko A. T. W., Ho, Cynthia K. Y., Geissler, Judy, Swelsen, Wendy T. N., Moorhouse, Michael J., Lardy, Neubury M., Roos, Dirk, van den Berg, Timo K., Kuijpers, Taco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695908/
https://www.ncbi.nlm.nih.gov/pubmed/23840750
http://dx.doi.org/10.1371/journal.pone.0067619

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