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Functional Complementation of a Model Target to Study Vpu Sensitivity

HIV-1 forms infectious particles with Murine Leukemia virus (MLV) Env, but not with the closely related Gibbon ape Leukemia Virus (GaLV) Env. We have determined that the incompatibility between HIV-1 and GaLV Env is primarily caused by the HIV-1 accessory protein Vpu, which prevents GaLV Env from be...

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Detalles Bibliográficos
Autores principales: Janaka, Sanath Kumar, Faurot, Jared, Johnson, Marc C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695915/
https://www.ncbi.nlm.nih.gov/pubmed/23840857
http://dx.doi.org/10.1371/journal.pone.0068507