Cargando…

Palmitic Acid Induces Osteoblastic Differentiation in Vascular Smooth Muscle Cells through ACSL3 and NF-κB, Novel Targets of Eicosapentaenoic Acid

Free fatty acids (FFAs), elevated in metabolic syndrome and diabetes, play a crucial role in the development of atherosclerotic cardiovascular disease, and eicosapentaenoic acid (EPA) counteracts many aspects of FFA-induced vascular pathology. Although vascular calcification is invariably associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kageyama, Aiko, Matsui, Hiroki, Ohta, Masahiko, Sambuichi, Keisuke, Kawano, Hiroyuki, Notsu, Tatsuto, Imada, Kazunori, Yokoyama, Tomoyuki, Kurabayashi, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695932/ https://www.ncbi.nlm.nih.gov/pubmed/23840832 http://dx.doi.org/10.1371/journal.pone.0068197

Ejemplares similares

Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet–Induced Obesity: Importance of Hepatic Lipogenesis
por: Sato, Ayumi, et al.
Publicado: (2010)

Antiapoptotic and Antiautophagic Effects of Eicosapentaenoic Acid in Cardiac Myoblasts Exposed to Palmitic Acid
por: Cetrullo, Silvia, et al.
Publicado: (2012)

Effects of palmitic acid and eicosapentaenoic acid on angiogenesis of porcine vascular endothelial cells
por: Peng, Jie, et al.
Publicado: (2021)

Eicosapentaenoic Acid Protects against Palmitic Acid-Induced Endothelial Dysfunction via Activation of the AMPK/eNOS Pathway
por: Lee, Che-Hsin, et al.
Publicado: (2014)

Suppression of Wnt Signaling and Osteogenic Changes in Vascular Smooth Muscle Cells by Eicosapentaenoic Acid
por: Saito, Yukihiro, et al.
Publicado: (2017)

Role of ACSL5 in fatty acid metabolism
por: Luo, Qin, et al.
Publicado: (2023)

Elongation of Long‐Chain Fatty Acid Family Member 6 (Elovl6)‐Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP‐Activated Protein Kinase/Krüppel‐Like Factor 4 (AMPK/KLF4) Signaling
por: Sunaga, Hiroaki, et al.
Publicado: (2016)

Oleic Acid and Eicosapentaenoic Acid Reverse Palmitic Acid-induced Insulin Resistance in Human HepG2 Cells via the Reactive Oxygen Species/JUN Pathway
por: Sun, Yaping, et al.
Publicado: (2021)

Docosahexaenoic and Eicosapentaenoic Acids Prevent Altered-Muc2 Secretion Induced by Palmitic Acid by Alleviating Endoplasmic Reticulum Stress in LS174T Goblet Cells
por: Escoula, Quentin, et al.
Publicado: (2019)

Effects of Eicosapentaenoic Acid on Arterial Calcification
por: Saito, Yukihiro, et al.
Publicado: (2020)

Cardiac Metabolism and Contractile Function in Mice with Reduced Trans-Endothelial Fatty Acid Transport
por: Iso, Tatsuya, et al.
Publicado: (2021)

Age Stratification and Impact of Eicosapentaenoic Acid and Docosahexaenoic Acid to Arachidonic Acid Ratios in Ischemic Stroke Patients
por: Ueno, Yuji, et al.
Publicado: (2018)

Docosahexaenoic acid and eicosapentaenoic acid strongly inhibit prostanoid TP receptor‐dependent contractions of guinea pig gastric fundus smooth muscle
por: Xu, Keyue, et al.
Publicado: (2022)

Distinguishing Health Benefits of Eicosapentaenoic and Docosahexaenoic Acids
por: Russell, Fraser D., et al.
Publicado: (2012)

Effects of sarpogrelate, eicosapentaenoic acid and pitavastatin on arterioslcerosis obliterans-related biomarkers in patients with type 2 diabetes (SAREPITASO study)
por: Nomura, Shosaku, et al.
Publicado: (2018)

The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells
por: Radif, Yassmeen, et al.
Publicado: (2018)

ACSL4 Directs Intramuscular Adipogenesis and Fatty Acid Composition in Pigs
por: Ren, Hongyan, et al.
Publicado: (2022)

The ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cancer death in a Japanese community: The Hisayama Study
por: Nagata, Masaharu, et al.
Publicado: (2017)

Fatty Acid Binding Protein 4 and 5 Play a Crucial Role in Thermogenesis under the Conditions of Fasting and Cold Stress
por: Syamsunarno, Mas Rizky A. A., et al.
Publicado: (2014)

ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
por: Yang, Yufei, et al.
Publicado: (2022)

Stearoyl-CoA Desaturase-1 (SCD1) Augments Saturated Fatty Acid-Induced Lipid Accumulation and Inhibits Apoptosis in Cardiac Myocytes
por: Matsui, Hiroki, et al.
Publicado: (2012)

Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) in Muscle Damage and Function
por: Ochi, Eisuke, et al.
Publicado: (2018)

Mechanisms of palmitate-induced cell death in human osteoblasts
por: Gunaratnam, Krishanthi, et al.
Publicado: (2013)

Eicosapentaenoic acid inhibits endothelial cell migration in vitro
por: Tonutti, Laura, et al.
Publicado: (2010)

Eicosapentaenoic acid attenuates obesity-related hepatocellular carcinogenesis
por: Inoue-Yamauchi, Akane, et al.
Publicado: (2018)

Eicosapentaenoic acid prevents the progression of intracranial aneurysms in rats
por: Abekura, Yu, et al.
Publicado: (2020)

Palmitate Impairs and Eicosapentaenoate Restores Insulin Secretion Through Regulation of SREBP-1c in Pancreatic Islets
por: Kato, Toyonori, et al.
Publicado: (2008)

Free Fatty Acid Palmitate Impairs the Vitality and Function of Cultured Human Bladder Smooth Muscle Cells
por: Oberbach, Andreas, et al.
Publicado: (2012)

Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1
por: Beatty, Alexander, et al.
Publicado: (2021)

Empagliflozin induces the transcriptional program for nutrient homeostasis in skeletal muscle in normal mice
por: Kawakami, Ryo, et al.
Publicado: (2023)

Individual variation and intraclass correlation in arachidonic acid and eicosapentaenoic acid in chicken muscle
por: Haug, Anna, et al.
Publicado: (2010)

The Role of Endogenous Eicosapentaenoic Acid and Docosahexaenoic Acid-Derived Resolvins in Systemic Sclerosis
por: Avanoǧlu Güler, Aslıhan, et al.
Publicado: (2020)

Emerging Mechanisms of Cardiovascular Protection for the Omega-3 Fatty Acid Eicosapentaenoic Acid
por: Mason, R. Preston, et al.
Publicado: (2020)

Association between Eicosapentaenoic Acid to Arachidonic Acid Ratio and Characteristics of Plaque Rupture
por: Sekimoto, Teruo, et al.
Publicado: (2023)

Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12
por: Cheon, Hyae Gyeong, et al.
Publicado: (2014)

Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy
por: Umbarawan, Yogi, et al.
Publicado: (2020)

Peroxisome Proliferator‐Activated Receptor‐γ in Capillary Endothelia Promotes Fatty Acid Uptake by Heart During Long‐Term Fasting
por: Goto, Kosaku, et al.
Publicado: (2013)

ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding
por: Al-Rashed, Fatema, et al.
Publicado: (2023)

Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells
por: Bate, Clive, et al.
Publicado: (2008)

Eicosapentaenoic Acid Suppresses the Proliferation of Synoviocytes from Rheumatoid Arthritis
por: Hamaguchi, Masahide, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_pcjufqg0j5lfabkatg2f9ko9sm