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Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1

BACKGROUND AND PURPOSE: Shikonin was reported to induce necroptosis in leukemia cells, but apoptosis in glioma cell lines. Thus, it is needed to clarify whether shikonin could cause necroptosis in glioma cells and investigate its underlying mechanisms. METHODS: Shikonin and rat C6 glioma cell line a...

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Detalles Bibliográficos
Autores principales:	Huang, Chuanjiang, Luo, Yinan, Zhao, Jingwei, Yang, Fuwei, Zhao, Hongwei, Fan, Wenhai, Ge, Pengfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695975/ https://www.ncbi.nlm.nih.gov/pubmed/23840441 http://dx.doi.org/10.1371/journal.pone.0066326

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