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Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds
Salmonella spp are a major foodborne zoonotic cause of human illness. Consumption of pork products is believed to be a major source of human salmonellosis and Salmonella control throughout the food-chain is recommended. A number of on-farm interventions have been proposed, and some have been impleme...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695987/ https://www.ncbi.nlm.nih.gov/pubmed/23840399 http://dx.doi.org/10.1371/journal.pone.0066054 |
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author | Berriman, Alexander D. C. Clancy, Damian Clough, Helen E. Armstrong, Derek Christley, Robert M. |
author_facet | Berriman, Alexander D. C. Clancy, Damian Clough, Helen E. Armstrong, Derek Christley, Robert M. |
author_sort | Berriman, Alexander D. C. |
collection | PubMed |
description | Salmonella spp are a major foodborne zoonotic cause of human illness. Consumption of pork products is believed to be a major source of human salmonellosis and Salmonella control throughout the food-chain is recommended. A number of on-farm interventions have been proposed, and some have been implemented in order to try to achieve Salmonella control. In this study we utilize previously developed models describing Salmonella dynamics to investigate the potential effects of a range of these on-farm interventions. As the models indicated that the number of bacteria shed in the faeces of an infectious animal was a key factor, interventions applied within a high-shedding scenario were also analysed. From simulation of the model, the probability of infection after Salmonella exposure was found to be a key driver of Salmonella transmission. The model also highlighted that minimising physiological stress can have a large effect but only when shedding levels are not excessive. When shedding was high, weekly cleaning and disinfection was not effective in Salmonella control. However it is possible that cleaning may have an effect if conducted more often. Furthermore, separating infectious animals, shedding bacteria at a high rate, from the rest of the population was found to be able to minimise the spread of Salmonella. |
format | Online Article Text |
id | pubmed-3695987 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-36959872013-07-09 Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds Berriman, Alexander D. C. Clancy, Damian Clough, Helen E. Armstrong, Derek Christley, Robert M. PLoS One Research Article Salmonella spp are a major foodborne zoonotic cause of human illness. Consumption of pork products is believed to be a major source of human salmonellosis and Salmonella control throughout the food-chain is recommended. A number of on-farm interventions have been proposed, and some have been implemented in order to try to achieve Salmonella control. In this study we utilize previously developed models describing Salmonella dynamics to investigate the potential effects of a range of these on-farm interventions. As the models indicated that the number of bacteria shed in the faeces of an infectious animal was a key factor, interventions applied within a high-shedding scenario were also analysed. From simulation of the model, the probability of infection after Salmonella exposure was found to be a key driver of Salmonella transmission. The model also highlighted that minimising physiological stress can have a large effect but only when shedding levels are not excessive. When shedding was high, weekly cleaning and disinfection was not effective in Salmonella control. However it is possible that cleaning may have an effect if conducted more often. Furthermore, separating infectious animals, shedding bacteria at a high rate, from the rest of the population was found to be able to minimise the spread of Salmonella. Public Library of Science 2013-06-28 /pmc/articles/PMC3695987/ /pubmed/23840399 http://dx.doi.org/10.1371/journal.pone.0066054 Text en © 2013 Berriman et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Berriman, Alexander D. C. Clancy, Damian Clough, Helen E. Armstrong, Derek Christley, Robert M. Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds |
title | Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds |
title_full | Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds |
title_fullStr | Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds |
title_full_unstemmed | Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds |
title_short | Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of Salmonella in UK Pig Herds |
title_sort | effectiveness of simulated interventions in reducing the estimated prevalence of salmonella in uk pig herds |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695987/ https://www.ncbi.nlm.nih.gov/pubmed/23840399 http://dx.doi.org/10.1371/journal.pone.0066054 |
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