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Mechanisms of Siglec-F-Induced Eosinophil Apoptosis: A Role for Caspases but Not for SHP-1, Src Kinases, NADPH Oxidase or Reactive Oxygen

BACKGROUND: Siglec-F and Siglec-8 are functional paralog proapoptotic cell surface receptors expressed on mouse and human eosinophils, respectively. Whereas Siglec-8 mediated death involves caspases and/or reactive oxygen species (ROS) generation and mitochondrial injury, very little is known about...

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Detalles Bibliográficos
Autores principales:	Mao, Hui, Kano, Gen, Hudson, Sherry A., Brummet, Mary, Zimmermann, Nives, Zhu, Zhou, Bochner, Bruce S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695997/ https://www.ncbi.nlm.nih.gov/pubmed/23840825 http://dx.doi.org/10.1371/journal.pone.0068143

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