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Congenic Mice Provide Evidence for a Genetic Locus That Modulates Spontaneous Arthritis Caused by Deficiency of IL-1RA

To understand the role of genetic factors involved in the development of spontaneous arthritis in mice deficient in IL-1 receptor antagonist protein (IL_1RA), we have identified a genomic region containing a major quantitative trait locus (QTL) for this disease. The QTL is on chromosome 1 and appear...

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Detalles Bibliográficos
Autores principales:	Cao, Yanhong, Liu, Xiaoyun, Deng, Nan, Jiao, Yan, Ma, Yonghui, Hasty, Karen A., Stuart, John M., Gu, Weikuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695999/ https://www.ncbi.nlm.nih.gov/pubmed/23840826 http://dx.doi.org/10.1371/journal.pone.0068158

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