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HLA Haplotyping from RNA-seq Data Using Hierarchical Read Weighting

Correctly matching the HLA haplotypes of donor and recipient is essential to the success of allogenic hematopoietic stem cell transplantation. Current HLA typing methods rely on targeted testing of recognized antigens or sequences. Despite advances in Next Generation Sequencing, general high through...

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Detalles Bibliográficos
Autores principales: Kim, Hyunsung John, Pourmand, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696101/
https://www.ncbi.nlm.nih.gov/pubmed/23840783
http://dx.doi.org/10.1371/journal.pone.0067885