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Hsp70 Oligomerization Is Mediated by an Interaction between the Interdomain Linker and the Substrate-Binding Domain
Oligomerization in the heat shock protein (Hsp) 70 family has been extensively documented both in vitro and in vivo, although the mechanism, the identity of the specific protein regions involved and the physiological relevance of this process are still unclear. We have studied the oligomeric propert...
Autores principales: | Aprile, Francesco A., Dhulesia, Anne, Stengel, Florian, Roodveldt, Cintia, Benesch, Justin L. P., Tortora, Paolo, Robinson, Carol V., Salvatella, Xavier, Dobson, Christopher M., Cremades, Nunilo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696110/ https://www.ncbi.nlm.nih.gov/pubmed/23840795 http://dx.doi.org/10.1371/journal.pone.0067961 |
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