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Human Thromboxane A(2) Receptor Genetic Variants: In Silico, In Vitro and “In Platelet” Analysis
Thromboxane and its receptor have emerged as key players in modulating vascular thrombotic events. Thus, a dysfunctional hTP genetic variant may protect against (hypoactivity) or promote (hyperactivity) vascular events, based upon its activity on platelets. After extensive in silico analysis, six hT...
Autores principales: | Gleim, Scott, Stitham, Jeremiah, Tang, Wai Ho, Li, Hong, Douville, Karen, Chelikani, Prashen, J.Rade, Jeffrey, Martin, Kathleen A., Hwa, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696120/ https://www.ncbi.nlm.nih.gov/pubmed/23840660 http://dx.doi.org/10.1371/journal.pone.0067314 |
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