Cargando…

Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia

Doxorubicin (Dox) is an antineoplastic agent used in a wide variety of malignancies. Its use is limited because of a cumulative, dose-dependent irreversible cardiomyopathy. We report a case of Dox induced cardiomyopathy, posted for modified radical mastectomy. The patient had poor LV function along...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Anuj, Kishore, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696268/
https://www.ncbi.nlm.nih.gov/pubmed/23825820
http://dx.doi.org/10.4103/0019-5049.111852
_version_ 1782476312386994176
author Jain, Anuj
Kishore, Kamal
author_facet Jain, Anuj
Kishore, Kamal
author_sort Jain, Anuj
collection PubMed
description Doxorubicin (Dox) is an antineoplastic agent used in a wide variety of malignancies. Its use is limited because of a cumulative, dose-dependent irreversible cardiomyopathy. We report a case of Dox induced cardiomyopathy, posted for modified radical mastectomy. The patient had poor LV function along with moderate pulmonary hypertension. Regional anaesthesia was planned as the risk associated with general anaesthesia was more. A cervical epidural was placed and a block adequate for surgery could be achived. The haemodynamic parameters as measured by esophageal doppler showed a stable trend. The surgery could be managed well under cervical epidural and also provided a good postoperative pain relief.
format Online
Article
Text
id pubmed-3696268
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-36962682013-07-03 Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia Jain, Anuj Kishore, Kamal Indian J Anaesth Case Report Doxorubicin (Dox) is an antineoplastic agent used in a wide variety of malignancies. Its use is limited because of a cumulative, dose-dependent irreversible cardiomyopathy. We report a case of Dox induced cardiomyopathy, posted for modified radical mastectomy. The patient had poor LV function along with moderate pulmonary hypertension. Regional anaesthesia was planned as the risk associated with general anaesthesia was more. A cervical epidural was placed and a block adequate for surgery could be achived. The haemodynamic parameters as measured by esophageal doppler showed a stable trend. The surgery could be managed well under cervical epidural and also provided a good postoperative pain relief. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3696268/ /pubmed/23825820 http://dx.doi.org/10.4103/0019-5049.111852 Text en Copyright: © Indian Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jain, Anuj
Kishore, Kamal
Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia
title Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia
title_full Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia
title_fullStr Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia
title_full_unstemmed Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia
title_short Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia
title_sort doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: a case managed under cervical epidural anaesthesia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696268/
https://www.ncbi.nlm.nih.gov/pubmed/23825820
http://dx.doi.org/10.4103/0019-5049.111852
work_keys_str_mv AT jainanuj doxorubicininduceddilatedcardiomyopathyformodifiedradicalmastectomyacasemanagedundercervicalepiduralanaesthesia
AT kishorekamal doxorubicininduceddilatedcardiomyopathyformodifiedradicalmastectomyacasemanagedundercervicalepiduralanaesthesia