Zeb1 Regulates E-cadherin and Epcam (Epithelial Cell Adhesion Molecule) Expression to Control Cell Behavior in Early Zebrafish Development

The ZEB1 transcription factor is best known as an inducer of epithelial-mesenchymal transitions (EMT) in cancer metastasis, acting through transcriptional repression of CDH1 (encoding E-cadherin) and the EMT-suppressing microRNA-200s (miR-200s). Here we analyze roles of the ZEB1 zebrafish orthologs,...

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Detalles Bibliográficos
Autores principales: Vannier, Corinne, Mock, Kerstin, Brabletz, Thomas, Driever, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696638/
https://www.ncbi.nlm.nih.gov/pubmed/23667256
http://dx.doi.org/10.1074/jbc.M113.467787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696638/
https://www.ncbi.nlm.nih.gov/pubmed/23667256
http://dx.doi.org/10.1074/jbc.M113.467787

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