Cargando…

Zeb1 Regulates E-cadherin and Epcam (Epithelial Cell Adhesion Molecule) Expression to Control Cell Behavior in Early Zebrafish Development

The ZEB1 transcription factor is best known as an inducer of epithelial-mesenchymal transitions (EMT) in cancer metastasis, acting through transcriptional repression of CDH1 (encoding E-cadherin) and the EMT-suppressing microRNA-200s (miR-200s). Here we analyze roles of the ZEB1 zebrafish orthologs,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vannier, Corinne, Mock, Kerstin, Brabletz, Thomas, Driever, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696638/ https://www.ncbi.nlm.nih.gov/pubmed/23667256 http://dx.doi.org/10.1074/jbc.M113.467787

Ejemplares similares

The Epithelial Cell Adhesion Molecule EpCAM Is Required for Epithelial Morphogenesis and Integrity during Zebrafish Epiboly and Skin Development
por: Slanchev, Krasimir, et al.
Publicado: (2009)

Regulation of cell–cell adhesion in prostate cancer cells by microRNA-96 through upregulation of E-Cadherin and EpCAM
por: Voss, Gjendine, et al.
Publicado: (2020)

The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors
por: Mock, Kerstin, et al.
Publicado: (2015)

Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions
por: Joy-Immediato, Michelle, et al.
Publicado: (2021)

Epithelial cell adhesion molecule (EpCAM) is involved in prostate cancer chemotherapy/radiotherapy response in vivo
por: Ni, Jie, et al.
Publicado: (2018)

Expression and function of epithelial cell adhesion molecule EpCAM: where are we after 40 years?
por: Gires, Olivier, et al.
Publicado: (2020)

Epithelial Cell Adhesion Molecule (EpCAM) Expression Can Be Modulated via NFκB
por: Zia, Saadiya, et al.
Publicado: (2022)

A novel mechanism of gland formation in zebrafish involving transdifferentiation of renal epithelial cells and live cell extrusion
por: Naylor, Richard W, et al.
Publicado: (2018)

Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells
por: Lasierra Losada, María, et al.
Publicado: (2021)

The Roles of Junctional Adhesion Molecules (JAMs) in Cell Migration
por: Wang, Junqi, et al.
Publicado: (2022)

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types
por: Lehmann, Waltraut, et al.
Publicado: (2016)

Laser Ablation of the Zebrafish Pronephros to Study Renal Epithelial Regeneration
por: Johnson, Corbin S., et al.
Publicado: (2011)

Targeted Methylation of the Epithelial Cell Adhesion Molecule (EpCAM) Promoter to Silence Its Expression in Ovarian Cancer Cells
por: Nunna, Suneetha, et al.
Publicado: (2014)

Immunohistochemical Expression of Epithelial Cell Adhesion Molecule (EpCAM) in Salivary Gland Cancer: Correlation with the Biological Behavior
por: Kalaitsidou, Ioanna, et al.
Publicado: (2023)

Epithelial cell adhesion molecule (EpCAM) regulates HGFR signaling to promote colon cancer progression and metastasis
por: Lee, Chi-Chiu, et al.
Publicado: (2023)

Plasticity in epithelial cell phenotype: modulation by expression of different cadherin cell adhesion molecules
Publicado: (1995)

Neural Stem Cell Regulation by Adhesion Molecules Within the Subependymal Niche
por: Morante-Redolat, Jose Manuel, et al.
Publicado: (2019)

Functional and Clinical Characteristics of Cell Adhesion Molecule CADM1 in Cancer
por: Li, Hongxu, et al.
Publicado: (2021)

Single Cell Fate Mapping in Zebrafish
por: Kohli, Vikram, et al.
Publicado: (2011)

Efficacy and Feasibility of the Epithelial Cell Adhesion Molecule (EpCAM) Immunomagnetic Cell Sorter for Studies of DNA Methylation in Colorectal Cancer
por: Failli, Alessandra, et al.
Publicado: (2013)

EpCAM as a Novel Biomarker for Survivals in Prostate Cancer Patients
por: Liao, Yang, et al.
Publicado: (2022)

A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos
por: Poureetezadi, Shahram Jevin, et al.
Publicado: (2014)

Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1
por: Omar, Fatma A., et al.
Publicado: (2023)

Reciprocal Interactions between Cell Adhesion Molecules of the Immunoglobulin Superfamily and the Cytoskeleton in Neurons
por: Leshchyns'ka, Iryna, et al.
Publicado: (2016)

Pathogenic Actions of Cell Adhesion Molecule 1 in Pulmonary Emphysema and Atopic Dermatitis
por: Yoneshige, Azusa, et al.
Publicado: (2015)

Editorial: From Structure to Function - The Interplay Between Cell Adhesion Molecules and the Cytoskeleton
por: Sytnyk, Vladimir, et al.
Publicado: (2020)

Mechanotransduction through adhesion molecules: Emerging roles in regulating the stem cell niche
por: Lim, Ryan, et al.
Publicado: (2022)

Epithelial Cell Adhesion Molecule (Ep-CAM) Modulates Cell–Cell Interactions Mediated by Classic Cadherins
por: Litvinov, Sergey V., et al.
Publicado: (1997)

Editorial: Investigating the Factors that Control Epithelial Cell Polarity and Adhesion During Morphogenesis
por: González-Mariscal, Lorenza
Publicado: (2021)

Junctional Adhesion Molecule 3 Expression in the Mouse Airway Epithelium Is Linked to Multiciliated Cells
por: Mateos-Quiros, Clara Maria, et al.
Publicado: (2021)

EpCAM-Mediated Cellular Plasticity Promotes Radiation Resistance and Metastasis in Breast Cancer
por: Mal, Arijit, et al.
Publicado: (2021)

ZEB1 in Pancreatic Cancer
por: Wellner, Ulrich, et al.
Publicado: (2010)

Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95
por: Frank, Daniel F., et al.
Publicado: (2017)

Lifelong regeneration of cerebellar Purkinje cells after induced cell ablation in zebrafish
por: Pose-Méndez, Sol, et al.
Publicado: (2023)

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer
por: Preca, Bogdan-Tiberius, et al.
Publicado: (2017)

HOTTIP-miR-205-ZEB2 Axis Confers Cisplatin Resistance to Ovarian Cancer Cells
por: Dong, Yu-Jie, et al.
Publicado: (2021)

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition
por: Singh, Shalini, et al.
Publicado: (2016)

Lens Fibrosis: Understanding the Dynamics of Cell Adhesion Signaling in Lens Epithelial-Mesenchymal Transition
por: Taiyab, Aftab, et al.
Publicado: (2022)

Expression and Function of Neuron-Glia-Related Cell Adhesion Molecule (NrCAM) in the Amygdalar Pathway
por: Mohan, Vishwa, et al.
Publicado: (2019)

Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration
por: Mitsogiannis, Manuela D., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_96f3gsof8pg8r68ca2nrgq323j