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Global probabilistic annotation of metabolic networks enables enzyme discovery

Annotation of organism-specific metabolic networks is one of the main challenges of systems biology. Importantly, due to inherent uncertainty of computational annotations, predictions of biochemical function need to be treated probabilistically. We present a global probabilistic approach to annotate...

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Detalles Bibliográficos
Autores principales: Plata, Germán, Fuhrer, Tobias, Hsiao, Tzu-Lin, Sauer, Uwe, Vitkup, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696893/
https://www.ncbi.nlm.nih.gov/pubmed/22960854
http://dx.doi.org/10.1038/nchembio.1063

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