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Global probabilistic annotation of metabolic networks enables enzyme discovery
Annotation of organism-specific metabolic networks is one of the main challenges of systems biology. Importantly, due to inherent uncertainty of computational annotations, predictions of biochemical function need to be treated probabilistically. We present a global probabilistic approach to annotate...
Autores principales: | Plata, Germán, Fuhrer, Tobias, Hsiao, Tzu-Lin, Sauer, Uwe, Vitkup, Dennis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696893/ https://www.ncbi.nlm.nih.gov/pubmed/22960854 http://dx.doi.org/10.1038/nchembio.1063 |
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