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Synaptic transmission and the susceptibility of HIV infection to anti-viral drugs
Cell-to-cell viral transmission via virological synapses has been argued to reduce susceptibility of the virus population to anti-viral drugs through multiple infection of cells, contributing to low-level viral persistence during therapy. Using a mathematical framework, we examine the role of synapt...
Autores principales: | Komarova, Natalia L., Levy, David N., Wodarz, Dominik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696900/ https://www.ncbi.nlm.nih.gov/pubmed/23811684 http://dx.doi.org/10.1038/srep02103 |
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