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Fetal Brain-directed AAV Gene Therapy Results in Rapid, Robust, and Persistent Transduction of Mouse Choroid Plexus Epithelia
Fetal brain-directed gene addition represents an under-appreciated tool for investigating novel therapeutic approaches in animal models of central nervous system diseases with early prenatal onset. Choroid plexuses (CPs) are specialized neuroectoderm-derived structures that project into the brain...
Autores principales: | Haddad, Marie Reine, Donsante, Anthony, Zerfas, Patricia, Kaler, Stephen G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696907/ https://www.ncbi.nlm.nih.gov/pubmed/23799375 http://dx.doi.org/10.1038/mtna.2013.27 |
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