Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment

The present work aimed at the development and application of a lipid-based nanocarrier for targeted delivery of nucleic acids to glioblastoma (GBM). For this purpose, chlorotoxin (CTX), a peptide reported to bind selectively to glioma cells while showing no affinity for non-neoplastic cells, was cov...

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Detalles Bibliográficos
Autores principales: Costa, Pedro M, Cardoso, Ana L, Mendonça, Liliana S, Serani, Angelo, Custódia, Carlos, Conceição, Mariana, Simões, Sérgio, Moreira, João N, Pereira de Almeida, Luís, Pedroso de Lima, Maria C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696908/
https://www.ncbi.nlm.nih.gov/pubmed/23778499
http://dx.doi.org/10.1038/mtna.2013.30

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