Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens

Varicella-zoster virus (VZV) vaccines induce immunity against childhood chickenpox and against shingles in older adults. The safety, efficacy, and widespread use of VZV vaccines suggest that they may also be effective as recombinant vaccines against other infectious diseases that affect the young an...

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Detalles Bibliográficos
Autor principal: Gray, Wayne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697282/
https://www.ncbi.nlm.nih.gov/pubmed/23843791
http://dx.doi.org/10.1155/2013/219439
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author Gray, Wayne L.
author_facet Gray, Wayne L.
author_sort Gray, Wayne L.
collection PubMed
description Varicella-zoster virus (VZV) vaccines induce immunity against childhood chickenpox and against shingles in older adults. The safety, efficacy, and widespread use of VZV vaccines suggest that they may also be effective as recombinant vaccines against other infectious diseases that affect the young and the elderly. The generation of recombinant VZV vaccines and their evaluation in animal models are reviewed. The potential advantages and limitations of recombinant VZV vaccines are addressed.
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spelling pubmed-36972822013-07-10 Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens Gray, Wayne L. Adv Virol Review Article Varicella-zoster virus (VZV) vaccines induce immunity against childhood chickenpox and against shingles in older adults. The safety, efficacy, and widespread use of VZV vaccines suggest that they may also be effective as recombinant vaccines against other infectious diseases that affect the young and the elderly. The generation of recombinant VZV vaccines and their evaluation in animal models are reviewed. The potential advantages and limitations of recombinant VZV vaccines are addressed. Hindawi Publishing Corporation 2013 2013-06-13 /pmc/articles/PMC3697282/ /pubmed/23843791 http://dx.doi.org/10.1155/2013/219439 Text en Copyright © 2013 Wayne L. Gray. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Gray, Wayne L.
Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens
title Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens
title_full Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens
title_fullStr Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens
title_full_unstemmed Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens
title_short Recombinant Varicella-Zoster Virus Vaccines as Platforms for Expression of Foreign Antigens
title_sort recombinant varicella-zoster virus vaccines as platforms for expression of foreign antigens
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697282/
https://www.ncbi.nlm.nih.gov/pubmed/23843791
http://dx.doi.org/10.1155/2013/219439
work_keys_str_mv AT graywaynel recombinantvaricellazostervirusvaccinesasplatformsforexpressionofforeignantigens

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