Cucurbitane Triterpenoid from Momordica charantia Induces Apoptosis and Autophagy in Breast Cancer Cells, in Part, through Peroxisome Proliferator-Activated Receptor γ Activation

Although the antitumor activity of the crude extract of wild bitter gourd (Momordica charantia L.) has been reported, its bioactive constituents and the underlying mechanism remain undefined. Here, we report that 3β,7β-dihydroxy-25-methoxycucurbita-5,23-diene-19-al (DMC), a cucurbitane-type triterpe...

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Detalles Bibliográficos
Autores principales: Weng, Jing-Ru, Bai, Li-Yuan, Chiu, Chang-Fang, Hu, Jing-Lan, Chiu, Shih-Jiuan, Wu, Chia-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697288/
https://www.ncbi.nlm.nih.gov/pubmed/23843889
http://dx.doi.org/10.1155/2013/935675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697288/
https://www.ncbi.nlm.nih.gov/pubmed/23843889
http://dx.doi.org/10.1155/2013/935675

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