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Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle

INTRODUCTION: Individuals with obesity and type 2 diabetes (T2D) are typically insulin resistant, exhibiting impaired skeletal muscle glucose uptake. Animal and cell culture experiments have shown that site-specific phosphorylation of the Rab-GTPase-activating proteins AS160 and TBC1D1 is critical f...

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Detalles Bibliográficos
Autores principales:	Middelbeek, R J W, Chambers, M A, Tantiwong, P, Treebak, J T, An, D, Hirshman, M F, Musi, N, Goodyear, L J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697402/ https://www.ncbi.nlm.nih.gov/pubmed/23752133 http://dx.doi.org/10.1038/nutd.2013.13

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