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Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors
BACKGROUND: High mobility group protein box 1 (HMGB1) is a DNA binding protein located in nucleus. It is released into extracellular fluid where it acts as a novel proinflammatory cytokine which interacts with Toll like receptor 4 (TLR4) to activate nuclear factor-κB (NF-κB). This sequence of events...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697986/ https://www.ncbi.nlm.nih.gov/pubmed/23803172 http://dx.doi.org/10.1186/1471-2407-13-311 |