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Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design
BACKGROUND: Health-Related Quality of Life (HRQoL) and functional exercise capacity are important area of therapeutic interventions needed to improve the general health of People Living with HIV/AIDS (PLWH). However, the relationship between self-report and Performance-based Measure of Functional Ca...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698161/ https://www.ncbi.nlm.nih.gov/pubmed/23802924 http://dx.doi.org/10.1186/1477-7525-11-106 |
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author | Mbada, Chidozie Emmanuel Onayemi, Olaniyi Ogunmoyole, Yewande Johnson, Olubusola Esther Akosile, Christopher O |
author_facet | Mbada, Chidozie Emmanuel Onayemi, Olaniyi Ogunmoyole, Yewande Johnson, Olubusola Esther Akosile, Christopher O |
author_sort | Mbada, Chidozie Emmanuel |
collection | PubMed |
description | BACKGROUND: Health-Related Quality of Life (HRQoL) and functional exercise capacity are important area of therapeutic interventions needed to improve the general health of People Living with HIV/AIDS (PLWH). However, the relationship between self-report and Performance-based Measure of Functional Capacity (PMFC) of PLWH is still obscure. This study compared the HRQoL and PMFC between a homogenous sample of clinical stage I PLWH and apparently healthy controls. METHODS: This case–control study involved 74 consenting participants (37 PLWH and 37 controls) who completed the self-report SF-12 questionnaire and PMFC assessment using Six Minute Walk Test (6MWT). PMFC was expressed in terms of Six-Minute Walk Distance (6MWD), Six-Minute Walk Work (6MWW) and Maximum oxygen uptake (VO(2)max). Data were analyzed using descriptive statistics of mean and inferential statistics of independent t-test, ANOVA and Pearson’s product moment correlation. Alpha level was set at 0.05. RESULTS: There was no significant difference in the SF-12 Physical-health Component Score (PCS) of PLWH and the controls (p = 0.782). However, the SF-12 Mental-health Component Score (MCS) of PLWH was higher than that of controls (p = 0.040). 6MWD, 6MWW and VO(2)max were significantly lower for PLWH (p < 0.05). Among PLWH, there was no significant gender differences in the PMFC (p > 0.05) while PCS was higher among females. There was no significant correlation between PMFC variables and each of PCS and MCS for PLWH and controls (p > 0.05) respectively. CONCLUSION: Self-report physical health of clinical stage 1 PLWH and controls was comparable, while self-report mental health capacity was higher in PLWH than the controls. PMFC of PLWH was significantly lower compared to healthy controls without gender bias. Overall, self-report and performance-based measure of physical functional capacity of PLWH was not inter-related. Therefore understanding the factors that may influence exercise capacity of PLWH may help to develop effective exercise programmes for PLWH. |
format | Online Article Text |
id | pubmed-3698161 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-36981612013-07-02 Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design Mbada, Chidozie Emmanuel Onayemi, Olaniyi Ogunmoyole, Yewande Johnson, Olubusola Esther Akosile, Christopher O Health Qual Life Outcomes Research BACKGROUND: Health-Related Quality of Life (HRQoL) and functional exercise capacity are important area of therapeutic interventions needed to improve the general health of People Living with HIV/AIDS (PLWH). However, the relationship between self-report and Performance-based Measure of Functional Capacity (PMFC) of PLWH is still obscure. This study compared the HRQoL and PMFC between a homogenous sample of clinical stage I PLWH and apparently healthy controls. METHODS: This case–control study involved 74 consenting participants (37 PLWH and 37 controls) who completed the self-report SF-12 questionnaire and PMFC assessment using Six Minute Walk Test (6MWT). PMFC was expressed in terms of Six-Minute Walk Distance (6MWD), Six-Minute Walk Work (6MWW) and Maximum oxygen uptake (VO(2)max). Data were analyzed using descriptive statistics of mean and inferential statistics of independent t-test, ANOVA and Pearson’s product moment correlation. Alpha level was set at 0.05. RESULTS: There was no significant difference in the SF-12 Physical-health Component Score (PCS) of PLWH and the controls (p = 0.782). However, the SF-12 Mental-health Component Score (MCS) of PLWH was higher than that of controls (p = 0.040). 6MWD, 6MWW and VO(2)max were significantly lower for PLWH (p < 0.05). Among PLWH, there was no significant gender differences in the PMFC (p > 0.05) while PCS was higher among females. There was no significant correlation between PMFC variables and each of PCS and MCS for PLWH and controls (p > 0.05) respectively. CONCLUSION: Self-report physical health of clinical stage 1 PLWH and controls was comparable, while self-report mental health capacity was higher in PLWH than the controls. PMFC of PLWH was significantly lower compared to healthy controls without gender bias. Overall, self-report and performance-based measure of physical functional capacity of PLWH was not inter-related. Therefore understanding the factors that may influence exercise capacity of PLWH may help to develop effective exercise programmes for PLWH. BioMed Central 2013-06-26 /pmc/articles/PMC3698161/ /pubmed/23802924 http://dx.doi.org/10.1186/1477-7525-11-106 Text en Copyright © 2013 Mbada et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Mbada, Chidozie Emmanuel Onayemi, Olaniyi Ogunmoyole, Yewande Johnson, Olubusola Esther Akosile, Christopher O Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design |
title | Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design |
title_full | Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design |
title_fullStr | Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design |
title_full_unstemmed | Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design |
title_short | Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design |
title_sort | health-related quality of life and physical functioning in people living with hiv/aids: a case–control design |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698161/ https://www.ncbi.nlm.nih.gov/pubmed/23802924 http://dx.doi.org/10.1186/1477-7525-11-106 |
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