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Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design

BACKGROUND: Health-Related Quality of Life (HRQoL) and functional exercise capacity are important area of therapeutic interventions needed to improve the general health of People Living with HIV/AIDS (PLWH). However, the relationship between self-report and Performance-based Measure of Functional Ca...

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Autores principales: Mbada, Chidozie Emmanuel, Onayemi, Olaniyi, Ogunmoyole, Yewande, Johnson, Olubusola Esther, Akosile, Christopher O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698161/
https://www.ncbi.nlm.nih.gov/pubmed/23802924
http://dx.doi.org/10.1186/1477-7525-11-106
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author Mbada, Chidozie Emmanuel
Onayemi, Olaniyi
Ogunmoyole, Yewande
Johnson, Olubusola Esther
Akosile, Christopher O
author_facet Mbada, Chidozie Emmanuel
Onayemi, Olaniyi
Ogunmoyole, Yewande
Johnson, Olubusola Esther
Akosile, Christopher O
author_sort Mbada, Chidozie Emmanuel
collection PubMed
description BACKGROUND: Health-Related Quality of Life (HRQoL) and functional exercise capacity are important area of therapeutic interventions needed to improve the general health of People Living with HIV/AIDS (PLWH). However, the relationship between self-report and Performance-based Measure of Functional Capacity (PMFC) of PLWH is still obscure. This study compared the HRQoL and PMFC between a homogenous sample of clinical stage I PLWH and apparently healthy controls. METHODS: This case–control study involved 74 consenting participants (37 PLWH and 37 controls) who completed the self-report SF-12 questionnaire and PMFC assessment using Six Minute Walk Test (6MWT). PMFC was expressed in terms of Six-Minute Walk Distance (6MWD), Six-Minute Walk Work (6MWW) and Maximum oxygen uptake (VO(2)max). Data were analyzed using descriptive statistics of mean and inferential statistics of independent t-test, ANOVA and Pearson’s product moment correlation. Alpha level was set at 0.05. RESULTS: There was no significant difference in the SF-12 Physical-health Component Score (PCS) of PLWH and the controls (p = 0.782). However, the SF-12 Mental-health Component Score (MCS) of PLWH was higher than that of controls (p = 0.040). 6MWD, 6MWW and VO(2)max were significantly lower for PLWH (p < 0.05). Among PLWH, there was no significant gender differences in the PMFC (p > 0.05) while PCS was higher among females. There was no significant correlation between PMFC variables and each of PCS and MCS for PLWH and controls (p > 0.05) respectively. CONCLUSION: Self-report physical health of clinical stage 1 PLWH and controls was comparable, while self-report mental health capacity was higher in PLWH than the controls. PMFC of PLWH was significantly lower compared to healthy controls without gender bias. Overall, self-report and performance-based measure of physical functional capacity of PLWH was not inter-related. Therefore understanding the factors that may influence exercise capacity of PLWH may help to develop effective exercise programmes for PLWH.
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spelling pubmed-36981612013-07-02 Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design Mbada, Chidozie Emmanuel Onayemi, Olaniyi Ogunmoyole, Yewande Johnson, Olubusola Esther Akosile, Christopher O Health Qual Life Outcomes Research BACKGROUND: Health-Related Quality of Life (HRQoL) and functional exercise capacity are important area of therapeutic interventions needed to improve the general health of People Living with HIV/AIDS (PLWH). However, the relationship between self-report and Performance-based Measure of Functional Capacity (PMFC) of PLWH is still obscure. This study compared the HRQoL and PMFC between a homogenous sample of clinical stage I PLWH and apparently healthy controls. METHODS: This case–control study involved 74 consenting participants (37 PLWH and 37 controls) who completed the self-report SF-12 questionnaire and PMFC assessment using Six Minute Walk Test (6MWT). PMFC was expressed in terms of Six-Minute Walk Distance (6MWD), Six-Minute Walk Work (6MWW) and Maximum oxygen uptake (VO(2)max). Data were analyzed using descriptive statistics of mean and inferential statistics of independent t-test, ANOVA and Pearson’s product moment correlation. Alpha level was set at 0.05. RESULTS: There was no significant difference in the SF-12 Physical-health Component Score (PCS) of PLWH and the controls (p = 0.782). However, the SF-12 Mental-health Component Score (MCS) of PLWH was higher than that of controls (p = 0.040). 6MWD, 6MWW and VO(2)max were significantly lower for PLWH (p < 0.05). Among PLWH, there was no significant gender differences in the PMFC (p > 0.05) while PCS was higher among females. There was no significant correlation between PMFC variables and each of PCS and MCS for PLWH and controls (p > 0.05) respectively. CONCLUSION: Self-report physical health of clinical stage 1 PLWH and controls was comparable, while self-report mental health capacity was higher in PLWH than the controls. PMFC of PLWH was significantly lower compared to healthy controls without gender bias. Overall, self-report and performance-based measure of physical functional capacity of PLWH was not inter-related. Therefore understanding the factors that may influence exercise capacity of PLWH may help to develop effective exercise programmes for PLWH. BioMed Central 2013-06-26 /pmc/articles/PMC3698161/ /pubmed/23802924 http://dx.doi.org/10.1186/1477-7525-11-106 Text en Copyright © 2013 Mbada et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Mbada, Chidozie Emmanuel
Onayemi, Olaniyi
Ogunmoyole, Yewande
Johnson, Olubusola Esther
Akosile, Christopher O
Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design
title Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design
title_full Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design
title_fullStr Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design
title_full_unstemmed Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design
title_short Health-related quality of life and physical functioning in people living with HIV/AIDS: a case–control design
title_sort health-related quality of life and physical functioning in people living with hiv/aids: a case–control design
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698161/
https://www.ncbi.nlm.nih.gov/pubmed/23802924
http://dx.doi.org/10.1186/1477-7525-11-106
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