Deletion of C7L and K1L Genes Leads to Significantly Decreased Virulence of Recombinant Vaccinia Virus TianTan

The vaccinia virus TianTan (VTT) has been modified as an HIV vaccine vector in China and has shown excellent performance in immunogenicity and safety. However, its adverse effects in immunosuppressed individuals warrant the search for a safer vector in the following clinic trails. In this study, we...

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Detalles Bibliográficos
Autores principales: Liu, Zheng, Wang, Shuhui, Zhang, Qicheng, Tian, Meijuan, Hou, Jue, Wang, Rongmin, Liu, Chang, Ji, Xu, Liu, Ying, Shao, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698190/
https://www.ncbi.nlm.nih.gov/pubmed/23840887
http://dx.doi.org/10.1371/journal.pone.0068115

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