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The LIM Homeodomain Protein Lhx6 Regulates Maturation of Interneurons and Network Excitability in the Mammalian Cortex
Deletion of LIM homeodomain transcription factor-encoding Lhx6 gene in mice results in defective tangential migration of cortical interneurons and failure of differentiation of the somatostatin (Sst)- and parvalbumin (Pva)-expressing subtypes. Here, we characterize a novel hypomorphic allele of Lhx6...
Autores principales: | Neves, Guilherme, Shah, Mala M., Liodis, Petros, Achimastou, Angeliki, Denaxa, Myrto, Roalfe, Grant, Sesay, Abdul, Walker, Matthew C., Pachnis, Vassilis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698365/ https://www.ncbi.nlm.nih.gov/pubmed/22710612 http://dx.doi.org/10.1093/cercor/bhs159 |
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