Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

Approximately 30 % of colorectal carcinomas develop via the serrated neoplasia pathway characterized by widespread DNA methylation and frequent BRAF mutation. Serrated polyps represent a heterogeneous group of polyps which are the precursor lesions to serrated pathway colorectal carcinomas. The hist...

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Detalles Bibliográficos
Autores principales: Rosty, Christophe, Hewett, David G., Brown, Ian S., Leggett, Barbara A., Whitehall, Vicki L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698429/
https://www.ncbi.nlm.nih.gov/pubmed/23208018
http://dx.doi.org/10.1007/s00535-012-0720-y

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