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Is abeta a sufficient biomarker for monitoring anti-abeta clinical studies? A critical review

Amyloid-beta (Aβ) in Alzheimer's disease (AD) appeared to be a promising target for disease-modifying therapeutic strategies like passive immunotherapy with anti-Aβ monoclonal antibodies (mAbs). Biochemical markers in cerebrospinal fluid (CSF) include alterations of Aβ that allow the diagnosis...

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Detalles Bibliográficos
Autores principales:	Moreth, Jens, Mavoungou, Chrystelle, Schindowski, Katharina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698450/ https://www.ncbi.nlm.nih.gov/pubmed/23847530 http://dx.doi.org/10.3389/fnagi.2013.00025

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