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Effects of Caffeine on Metabolism and Mitochondria Biogenesis in Rhabdomyosarcoma Cells Compared with 2,4-Dinitrophenol

PURPOSE: This work investigated if treatment with caffeine or 2,4-dinitrophenol (DNP) induce expression of peroxisome proliferator-activated receptor coactivator 1 alpha (PGC-1α) and increase both mitochondrial biosynthesis and metabolism in skeletal muscle. METHODS: Human rhabdomyosarcoma cells wer...

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Detalles Bibliográficos
Autores principales:	Vaughan, Roger A., Garcia-Smith, Randi, Bisoffi, Marco, Trujillo, Kristina A., Conn, Carole A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698477/ https://www.ncbi.nlm.nih.gov/pubmed/23882149 http://dx.doi.org/10.4137/NMI.S10233

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