Cargando…

DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types

DNase-seq is primarily used to identify nucleosome-depleted DNase I hypersensitive (DHS) sites genome-wide that correspond to active regulatory elements. However, ∼40 yr ago it was demonstrated that DNase I also digests with a ∼10-bp periodicity around nucleosomes matching the exposure of the DNA mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Winter, Deborah R., Song, Lingyun, Mukherjee, Sayan, Furey, Terrence S., Crawford, Gregory E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698505/
https://www.ncbi.nlm.nih.gov/pubmed/23657885
http://dx.doi.org/10.1101/gr.150482.112

Ejemplares similares