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AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer

The basic helix-loop-helix transcription factor AP4/TFAP4/AP-4 is encoded by a c-MYC target gene and displays up-regulation concomitantly with c-MYC in colorectal cancer (CRC) and numerous other tumor types. Here a genome-wide characterization of AP4 DNA binding and mRNA expression was performed usi...

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Detalles Bibliográficos
Autores principales: Jackstadt, Rene, Röh, Simone, Neumann, Jens, Jung, Peter, Hoffmann, Reinhard, Horst, David, Berens, Christian, Bornkamm, Georg W., Kirchner, Thomas, Menssen, Antje, Hermeking, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698521/
https://www.ncbi.nlm.nih.gov/pubmed/23752226
http://dx.doi.org/10.1084/jem.20120812

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