Identification of beryllium-dependent peptides recognized by CD4(+) T cells in chronic beryllium disease

Chronic beryllium disease (CBD) is a granulomatous disorder characterized by an influx of beryllium (Be)-specific CD4(+) T cells into the lung. The vast majority of these T cells recognize Be in an HLA-DP–restricted manner, and peptide is required for T cell recognition. However, the peptides that s...

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Detalles Bibliográficos
Autores principales: Falta, Michael T., Pinilla, Clemencia, Mack, Douglas G., Tinega, Alex N., Crawford, Frances, Giulianotti, Marc, Santos, Radleigh, Clayton, Gina M., Wang, Yuxiao, Zhang, Xuewu, Maier, Lisa A., Marrack, Philippa, Kappler, John W., Fontenot, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698527/
https://www.ncbi.nlm.nih.gov/pubmed/23797096
http://dx.doi.org/10.1084/jem.20122426

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