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Raiding the pharmacy: genomic screening identifies known chemotherapies as negative regulators of MCL1
Despite multiple studies demonstrating the importance of the anti-apoptotic protein Mcl-1 in tumor cell survival and treatment resistance, a clinically important inhibitor has yet to be developed. A recent study by Guo Wei and colleagues published in Cancer Cell has utilized a novel high-throughput...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698534/ https://www.ncbi.nlm.nih.gov/pubmed/22742055 http://dx.doi.org/10.1186/gm352 |