Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants

Plant-derived dietary antioxidants have attracted considerable interest in recent past for their chemopreventive and cancer therapeutic abilities in animal models. Thymoquinone (TQ) is the major bioactive constituent of volatile oil of Nigella sativa and has been shown to exert various pharmacologic...

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Detalles Bibliográficos
Autores principales: Zubair, H, Khan, H Y, Sohail, A, Azim, S, Ullah, M F, Ahmad, A, Sarkar, F H, Hadi, S M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698541/
https://www.ncbi.nlm.nih.gov/pubmed/23744360
http://dx.doi.org/10.1038/cddis.2013.172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698541/
https://www.ncbi.nlm.nih.gov/pubmed/23744360
http://dx.doi.org/10.1038/cddis.2013.172

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