Wentilactone B induces G2/M phase arrest and apoptosis via the Ras/Raf/MAPK signaling pathway in human hepatoma SMMC-7721 cells

Hepatocellular carcinoma (HCC) is generally acknowledged as the most common primary malignant tumor, and it is known to be resistant to conventional chemotherapy. Wentilactone B (WB), a tetranorditerpenoid derivative extracted from the marine algae-derived endophytic fungus Aspergillus wentii EN-48,...

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Detalles Bibliográficos
Autores principales: Zhang, Z, Miao, L, Lv, C, Sun, H, Wei, S, Wang, B, Huang, C, Jiao, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698549/
https://www.ncbi.nlm.nih.gov/pubmed/23744357
http://dx.doi.org/10.1038/cddis.2013.182

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