Cargando…
RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer's brain synaptosomes
We previously demonstrated that overexpression of RanBP9 led to enhanced Aβ generation in a variety of cell lines and primary neuronal cultures, and subsequently, we confirmed increased amyloid plaque burden in a mouse model of Alzheimer's disease (AD). In the present study, we found striking r...
Autores principales: | Palavicini, J P, Wang, H, Bianchi, E, Xu, S, Rao, J S, Kang, D E, Lakshmana, M K |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698550/ https://www.ncbi.nlm.nih.gov/pubmed/23764848 http://dx.doi.org/10.1038/cddis.2013.183 |
Ejemplares similares
-
RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice
por: Palavicini, Juan Pablo, et al.
Publicado: (2013) -
RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction
por: Woo, J A, et al.
Publicado: (2015) -
RanBP9 Overexpression Accelerates Loss of Pre and Postsynaptic Proteins in the APΔE9 Transgenic Mouse Brain
por: Wang, Hongjie, et al.
Publicado: (2014) -
RanBP2 Modulates Cox11 and Hexokinase I Activities and Haploinsufficiency of RanBP2 Causes Deficits in Glucose Metabolism
por: Aslanukov, Azamat, et al.
Publicado: (2006) -
Correction: RanBP9 Overexpression Accelerates Loss of Pre and Postsynaptic Proteins in the APΔE9 Transgenic Mouse Brain
por: Wang, Hongjie, et al.
Publicado: (2019)