Cargando…

Improved Survival After Heart Failure: A Community‐Based Perspective

BACKGROUND: Heart failure is a highly prevalent, morbid, and costly disease with a poor long‐term prognosis. Evidence‐based therapies utilized over the past 2 decades hold the promise of improved outcomes, yet few contemporary studies have examined survival trends in patients with acute heart failur...

Descripción completa

Detalles Bibliográficos
Autores principales: Joffe, Samuel W., Webster, Kristy, McManus, David D., Kiernan, Michael S., Lessard, Darleen, Yarzebski, Jorge, Darling, Chad, Gore, Joel M., Goldberg, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698761/
https://www.ncbi.nlm.nih.gov/pubmed/23676294
http://dx.doi.org/10.1161/JAHA.113.000053
_version_ 1782275328843972608
author Joffe, Samuel W.
Webster, Kristy
McManus, David D.
Kiernan, Michael S.
Lessard, Darleen
Yarzebski, Jorge
Darling, Chad
Gore, Joel M.
Goldberg, Robert J.
author_facet Joffe, Samuel W.
Webster, Kristy
McManus, David D.
Kiernan, Michael S.
Lessard, Darleen
Yarzebski, Jorge
Darling, Chad
Gore, Joel M.
Goldberg, Robert J.
author_sort Joffe, Samuel W.
collection PubMed
description BACKGROUND: Heart failure is a highly prevalent, morbid, and costly disease with a poor long‐term prognosis. Evidence‐based therapies utilized over the past 2 decades hold the promise of improved outcomes, yet few contemporary studies have examined survival trends in patients with acute heart failure. The primary objective of this population‐based study was to describe trends in short‐ and long‐term survival in patients hospitalized with acute decompensated heart failure (ADHF). A secondary objective was to examine patient characteristics associated with decreased long‐term survival. METHODS AND RESULTS: We reviewed the medical records of 9748 patients hospitalized with ADHF at all 11 medical centers in central Massachusetts during 1995, 2000, 2002, and 2004. Patients hospitalized with ADHF were more likely to be elderly and to have been diagnosed with multiple comorbidities in 2004 compared with 1995. Over this period, survival was significantly improved in‐hospital, and at 1, 2, and 5 years postdischarge. Five‐year survival rates increased from 20% in 1995 to 29% in 2004. Although survival improved substantially over time, older patients and patients with chronic kidney disease, chronic obstructive pulmonary disease, anemia, low body mass index, and low blood pressures had consistently lower postdischarge survival rates than patients without these comorbidities. CONCLUSION: Between 1995 and 2004, patients hospitalized with ADHF have become older and increasingly comorbid. Although there has been a significant improvement in survival among these patients, their long‐term prognosis remains poor, as fewer than 1 in 3 patients hospitalized with ADHF in 2004 survived more than 5 years.
format Online
Article
Text
id pubmed-3698761
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Blackwell Publishing Ltd
record_format MEDLINE/PubMed
spelling pubmed-36987612013-09-03 Improved Survival After Heart Failure: A Community‐Based Perspective Joffe, Samuel W. Webster, Kristy McManus, David D. Kiernan, Michael S. Lessard, Darleen Yarzebski, Jorge Darling, Chad Gore, Joel M. Goldberg, Robert J. J Am Heart Assoc Original Research BACKGROUND: Heart failure is a highly prevalent, morbid, and costly disease with a poor long‐term prognosis. Evidence‐based therapies utilized over the past 2 decades hold the promise of improved outcomes, yet few contemporary studies have examined survival trends in patients with acute heart failure. The primary objective of this population‐based study was to describe trends in short‐ and long‐term survival in patients hospitalized with acute decompensated heart failure (ADHF). A secondary objective was to examine patient characteristics associated with decreased long‐term survival. METHODS AND RESULTS: We reviewed the medical records of 9748 patients hospitalized with ADHF at all 11 medical centers in central Massachusetts during 1995, 2000, 2002, and 2004. Patients hospitalized with ADHF were more likely to be elderly and to have been diagnosed with multiple comorbidities in 2004 compared with 1995. Over this period, survival was significantly improved in‐hospital, and at 1, 2, and 5 years postdischarge. Five‐year survival rates increased from 20% in 1995 to 29% in 2004. Although survival improved substantially over time, older patients and patients with chronic kidney disease, chronic obstructive pulmonary disease, anemia, low body mass index, and low blood pressures had consistently lower postdischarge survival rates than patients without these comorbidities. CONCLUSION: Between 1995 and 2004, patients hospitalized with ADHF have become older and increasingly comorbid. Although there has been a significant improvement in survival among these patients, their long‐term prognosis remains poor, as fewer than 1 in 3 patients hospitalized with ADHF in 2004 survived more than 5 years. Blackwell Publishing Ltd 2013-06-21 /pmc/articles/PMC3698761/ /pubmed/23676294 http://dx.doi.org/10.1161/JAHA.113.000053 Text en © 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley-Blackwell. http://creativecommons.org/licenses/by/2.5/ This is an Open Access article under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Joffe, Samuel W.
Webster, Kristy
McManus, David D.
Kiernan, Michael S.
Lessard, Darleen
Yarzebski, Jorge
Darling, Chad
Gore, Joel M.
Goldberg, Robert J.
Improved Survival After Heart Failure: A Community‐Based Perspective
title Improved Survival After Heart Failure: A Community‐Based Perspective
title_full Improved Survival After Heart Failure: A Community‐Based Perspective
title_fullStr Improved Survival After Heart Failure: A Community‐Based Perspective
title_full_unstemmed Improved Survival After Heart Failure: A Community‐Based Perspective
title_short Improved Survival After Heart Failure: A Community‐Based Perspective
title_sort improved survival after heart failure: a community‐based perspective
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698761/
https://www.ncbi.nlm.nih.gov/pubmed/23676294
http://dx.doi.org/10.1161/JAHA.113.000053
work_keys_str_mv AT joffesamuelw improvedsurvivalafterheartfailureacommunitybasedperspective
AT websterkristy improvedsurvivalafterheartfailureacommunitybasedperspective
AT mcmanusdavidd improvedsurvivalafterheartfailureacommunitybasedperspective
AT kiernanmichaels improvedsurvivalafterheartfailureacommunitybasedperspective
AT lessarddarleen improvedsurvivalafterheartfailureacommunitybasedperspective
AT yarzebskijorge improvedsurvivalafterheartfailureacommunitybasedperspective
AT darlingchad improvedsurvivalafterheartfailureacommunitybasedperspective
AT gorejoelm improvedsurvivalafterheartfailureacommunitybasedperspective
AT goldbergrobertj improvedsurvivalafterheartfailureacommunitybasedperspective