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All or Nothing: Protein Complexes Flip Essentiality between Distantly Related Eukaryotes

In the budding yeast Saccharomyces cerevisiae, the subunits of any given protein complex are either mostly essential or mostly nonessential, suggesting that essentiality is a property of molecular machines rather than individual components. There are exceptions to this rule, however, that is, noness...

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Detalles Bibliográficos
Autores principales: Ryan, Colm J., Krogan, Nevan J., Cunningham, Pádraig, Cagney, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698920/
https://www.ncbi.nlm.nih.gov/pubmed/23661563
http://dx.doi.org/10.1093/gbe/evt074