Primary primitive neuroectodermal tumor of the cervix

Primary primitive neuroectodermal tumors (PNETs) are rare and high-grade malignant tumors that mostly occur in children and young adults. The most common sites are the trunk, limbs, and retroperitoneum. Herein, we present a case of a PNET involving the cervix uteri in a 27-year-old woman. The lesion...

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Autores principales: Li, Bo, Ouyang, Ling, Han, Xue, Zhou, Yang, Tong, Xin, Zhang, Shulang, Zhang, Qingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699316/
https://www.ncbi.nlm.nih.gov/pubmed/23836982
http://dx.doi.org/10.2147/OTT.S45889
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author Li, Bo
Ouyang, Ling
Han, Xue
Zhou, Yang
Tong, Xin
Zhang, Shulang
Zhang, Qingfu
author_facet Li, Bo
Ouyang, Ling
Han, Xue
Zhou, Yang
Tong, Xin
Zhang, Shulang
Zhang, Qingfu
author_sort Li, Bo
collection PubMed
description Primary primitive neuroectodermal tumors (PNETs) are rare and high-grade malignant tumors that mostly occur in children and young adults. The most common sites are the trunk, limbs, and retroperitoneum. Herein, we present a case of a PNET involving the cervix uteri in a 27-year-old woman. The lesion showed characteristic histologic features of a PNET and was positive for the immunohistochemical markers cluster of differentiation (CD) 99, vimentin, neuron-specific enolase, neural cell adhesion molecule 1 (CD56), and CD117 (c-kit), further defining the tumor while helping to confirm PNET. The clinical Stage IIIB tumor was treated with chemotherapy and radiotherapy.
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spelling pubmed-36993162013-07-08 Primary primitive neuroectodermal tumor of the cervix Li, Bo Ouyang, Ling Han, Xue Zhou, Yang Tong, Xin Zhang, Shulang Zhang, Qingfu Onco Targets Ther Case Report Primary primitive neuroectodermal tumors (PNETs) are rare and high-grade malignant tumors that mostly occur in children and young adults. The most common sites are the trunk, limbs, and retroperitoneum. Herein, we present a case of a PNET involving the cervix uteri in a 27-year-old woman. The lesion showed characteristic histologic features of a PNET and was positive for the immunohistochemical markers cluster of differentiation (CD) 99, vimentin, neuron-specific enolase, neural cell adhesion molecule 1 (CD56), and CD117 (c-kit), further defining the tumor while helping to confirm PNET. The clinical Stage IIIB tumor was treated with chemotherapy and radiotherapy. Dove Medical Press 2013-06-17 /pmc/articles/PMC3699316/ /pubmed/23836982 http://dx.doi.org/10.2147/OTT.S45889 Text en © 2013 Li et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Li, Bo
Ouyang, Ling
Han, Xue
Zhou, Yang
Tong, Xin
Zhang, Shulang
Zhang, Qingfu
Primary primitive neuroectodermal tumor of the cervix
title Primary primitive neuroectodermal tumor of the cervix
title_full Primary primitive neuroectodermal tumor of the cervix
title_fullStr Primary primitive neuroectodermal tumor of the cervix
title_full_unstemmed Primary primitive neuroectodermal tumor of the cervix
title_short Primary primitive neuroectodermal tumor of the cervix
title_sort primary primitive neuroectodermal tumor of the cervix
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699316/
https://www.ncbi.nlm.nih.gov/pubmed/23836982
http://dx.doi.org/10.2147/OTT.S45889
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