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Targeting of Acyl-CoA synthetase 5 decreases jejunal fatty acid activation with no effect on dietary long-chain fatty acid absorption

BACKGROUND: The absorption of dietary long chain fatty acids (LCFA) largely occurs in the jejunum. LCFA are activated via conjugation with Coenzyme A (CoA), a reaction catalyzed by Acyl-CoA synthetases (ACS). Acyl-CoA sythesis is critical for dietary LCFA absorption; yet, the jejunal ACS enzymes tha...

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Detalles Bibliográficos
Autores principales:	Meller, Nahum, Morgan, Michelle E, Wong, Winifred PS, Altemus, Jessica B, Sehayek, Ephraim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699395/ https://www.ncbi.nlm.nih.gov/pubmed/23767941 http://dx.doi.org/10.1186/1476-511X-12-88

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