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Engineered ascorbate peroxidase as a genetically-encoded reporter for electron microscopy
Electron microscopy (EM) is the standard method for imaging cellular structures with nanometer resolution, but existing genetic tags are inactive in most cellular compartments(1) or require light and are difficult to use(2). Here we report the development of a simple and robust EM genetic tag, calle...
Autores principales: | Martell, Jeffrey D., Deerinck, Thomas J., Sancak, Yasemin, Poulos, Thomas L., Mootha, Vamsi K., Sosinsky, Gina E., Ellisman, Mark H., Ting, Alice Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699407/ https://www.ncbi.nlm.nih.gov/pubmed/23086203 http://dx.doi.org/10.1038/nbt.2375 |
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