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Soluble ICAM-5, a Product of Activity Dependent Proteolysis, Increases mEPSC Frequency and Dendritic Expression of GluA1

Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases that can be released from neurons in an activity dependent manner to play a role in varied forms of learning and memory. MMP inhibitors impair hippocampal long term potentiation (LTP), spatial memory, and behavioral correlates of dru...

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Detalles Bibliográficos
Autores principales: Lonskaya, Irina, Partridge, John, Lalchandani, Rupa R., Chung, Andrew, Lee, Taehee, Vicini, Stefano, Hoe, Hyang-Sook, Lim, Seung T., Conant, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699500/
https://www.ncbi.nlm.nih.gov/pubmed/23844251
http://dx.doi.org/10.1371/journal.pone.0069136