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Protein Kinase R Modulates c-Fos and c-Jun Signaling to Promote Proliferation of Hepatocellular Carcinoma with Hepatitis C Virus Infection

Double-stranded RNA-activated protein kinase R (PKR) is known to be upregulated by hepatitis C virus (HCV) and overexpressed in hepatocellular carcinoma (HCC). However, the precise roles of PKR in HCC with HCV infection remain unclear. Two HCV replicating cell lines (JFH-1 and H77s), generated by tr...

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Detalles Bibliográficos
Autores principales:	Watanabe, Takao, Hiasa, Yoichi, Tokumoto, Yoshio, Hirooka, Masashi, Abe, Masanori, Ikeda, Yoshio, Matsuura, Bunzo, Chung, Raymond T., Onji, Morikazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699507/ https://www.ncbi.nlm.nih.gov/pubmed/23844083 http://dx.doi.org/10.1371/journal.pone.0067750

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