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δ-Opioid Receptor Activation Rescues the Functional TrkB Receptor and Protects the Brain from Ischemia-Reperfusion Injury in the Rat

OBJECTIVES: δ-opioid receptor (DOR) activation reduced brain ischemic infarction and attenuated neurological deficits, while DOR inhibition aggravated the ischemic damage. The underlying mechanisms are, however, not well understood yet. In this work, we asked if DOR activation protects the brain aga...

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Detalles Bibliográficos
Autores principales: Tian, Xuesong, Guo, Jingchun, Zhu, Min, Li, Minwei, Wu, Gencheng, Xia, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699518/
https://www.ncbi.nlm.nih.gov/pubmed/23844255
http://dx.doi.org/10.1371/journal.pone.0069252

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